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Publications

Research Publications

  • Suarez, C. M.; Talbot, F. O.; Jockusch, R. A. Characterization and Manipulation of Ion Clouds Inside an FT-ICR Instrument: A Laser Tomography Perspective. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY 2026, 37 (2), 413–423. https://doi.org/10.1021/jasms.5c00330
  • Talbot, F. O.; Suarez, C. M.; Nagy, A. M.; Chen, J. C.; Djavani-Tabrizi, I.; Clotea, I.; Jockusch, R. A. Robust Fluorescence Collection Module for Wide-Bore Ion Cyclotron Resonance Mass Spectrometers. ANALYTICAL CHEMISTRY 2023, 95 (47), 17193–17202. https://doi.org/10.1021/acs.analchem.3c01801
  • Djavani-Tabrizi, I.; Jockusch, R. A. Gas-Phase Fluorescence of Proflavine Reveals Two Close-Lying, Brightly Emitting States. JOURNAL OF PHYSICAL CHEMISTRY LETTERS 2022, 13 (9), 2187–2192. https://doi.org/10.1021/acs.jpclett.2c00201
  • Kung, J. C. K.; Vurgun, N.; Chen, J. C.; Nitz, M.; Jockusch, R. A. Intrinsic Turn-On Response of Thioflavin T in Complexes. CHEMISTRY-A EUROPEAN JOURNAL 2020, 26 (16), 3479–3483. https://doi.org/10.1002/chem.201905100
  • Chen, J. C.; Jockusch, R. A. Protomers of DNA-Binding Dye Fluoresce Different Colours: Intrinsic Photophysics of Hoechst 33258. PHYSICAL CHEMISTRY CHEMICAL PHYSICS 2019, 21 (30), 16848–16858. https://doi.org/10.1039/c9cp02421b
  • Kung, J. C. K.; Forman, A.; Jockusch, R. A. The Effect of Methylation on the Intrinsic Photophysical Properties of Simple Rhodamines. PHYSICAL CHEMISTRY CHEMICAL PHYSICS 2019, 21 (20), 10261–10271. https://doi.org/10.1039/c9cp00730j
  • Straus, R. N.; Jockusch, R. A. Hydrogen-Deuterium Exchange and Electron Capture Dissociation to Interrogate the Conformation of Gaseous Melittin Ions. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY 2019, 30 (5), 864–875. https://doi.org/10.1007/s13361-019-02150-5
  • Kusinski, M.; Nagesh, J.; Gladkikh, M.; Izmaylov, A. F.; Jockusch, R. A. Deuterium Isotope Effect in Fluorescence of Gaseous Oxazine Dyes. PHYSICAL CHEMISTRY CHEMICAL PHYSICS 2019, 21 (10), 5759–5770. https://doi.org/10.1039/c8cp05731a
  • Tiefenbach, J.; Magomedova, L.; Liu, J.; Reunov, A. A.; Tsai, R.; Eappen, N. S.; Jockusch, R. A.; Nislow, C.; Cummins, C. L.; Krause, H. M. Idebenone and Coenzyme Q10 Are Novel PPARα/γ Ligands, with Potential for Treatment of Fatty Liver Diseases. DISEASE MODELS & MECHANISMS 2018, 11 (9). https://doi.org/10.1242/dmm.034801
  • Wellman, S. M. J.; Jockusch, R. A. Tuning the Intrinsic Photophysical Properties of Chlorophyll a. CHEMISTRY-A EUROPEAN JOURNAL 2017, 23 (32), 7728–7736. https://doi.org/10.1002/chem.201605167
  • Straus, R. N.; Jockusch, R. A. Probing the Gaseous Structure of a β-Hairpin Peptide with H/D Exchange and Electron Capture Dissociation. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY 2017, 28 (2), 358–369. https://doi.org/10.1007/s13361-016-1528-4
  • Czar, M. F.; Jockusch, R. A. Sensitive Probes of Protein Structure and Dynamics in Well-Controlled Environments: Combining Mass Spectrometry with Fluorescence Spectroscopy. CURRENT OPINION IN STRUCTURAL BIOLOGY 2015, 34, 123–134. https://doi.org/10.1016/j.sbi.2015.09.004
  • Sciuto, S. V.; Jockusch, R. A. The Intrinsic Photophysics of Gaseous Ethidium Ions. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY 2015, 311, 186–192. https://doi.org/10.1016/j.jphotochem.2015.06.020
  • Czar, M. F.; Zosel, F.; Koenig, I.; Nettels, D.; Wunderlich, B.; Schuler, B.; Zarrine-Afsar, A.; Jockusch, R. A. Gas-Phase FRET Efficiency Measurements To Probe the Conformation of Mass-Selected Proteins. ANALYTICAL CHEMISTRY 2015, 87 (15), 7559–7565. https://doi.org/10.1021/acs.analchem.5b01591
  • Wellman, S. M. J.; Jockusch, R. A. Moving in on the Action: An Experimental Comparison of Fluorescence Excitation and Photodissociation Action Spectroscopy. JOURNAL OF PHYSICAL CHEMISTRY A 2015, 119 (24), 6333–6338. https://doi.org/10.1021/acs.jpca.5b04835
  • Jockusch, R. A. Fluorescence and FRET Measurements to Determine Properties of Mass-Selected Gaseous Ions. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2014, 247.
  • Talbot, F. O.; Sciuto, S. V.; Jockusch, R. A. Fluorescence Imaging for Visualization of the Ion Cloud in a Quadrupole Ion Trap Mass Spectrometer. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY 2013, 24 (12), 1823–1832. https://doi.org/10.1007/s13361-013-0742-6
  • Czar, M. F.; Jockusch, R. A. Understanding Photophysical Effects of Cucurbituril Encapsulation: A Model Study with Acridine Orange in the Gas Phase. CHEMPHYSCHEM 2013, 14 (6), 1138–1148. https://doi.org/10.1002/cphc.201201008
  • Yao, H.; Jockusch, R. A. Fluorescence and Electronic Action Spectroscopy of Mass-Selected Gas-Phase Fluorescein, 2′,7′-Dichlorofluorescein, and 2′,7′-Difluorofluorescein Ions. JOURNAL OF PHYSICAL CHEMISTRY A 2013, 117 (6), 1351–1359. https://doi.org/10.1021/jp309767f
  • Heath, B. L.; Jockusch, R. A. Ligand Migration in the Gaseous Insulin-CB7 Complex-A Cautionary Tale About the Use of ECD-MS for Ligand Binding Site Determination. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY 2012, 23 (11), 1911–1920. https://doi.org/10.1007/s13361-012-0470-3
  • Nagy, A. M.; Talbot, F. O.; Czar, M. F.; Jockusch, R. A. Fluorescence Lifetimes of Rhodamine Dyes in Vacuo. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY 2012, 244, 47–53. https://doi.org/10.1016/j.jphotochem.2012.06.017
  • Pan, J.; Heath, B. L.; Jockusch, R. A.; Konermann, L. Structural Interrogation of Electrosprayed Peptide Ions by Gas-Phase H/D Exchange and Electron Capture Dissociation Mass Spectrometry. ANALYTICAL CHEMISTRY 2012, 84 (1), 373–378. https://doi.org/10.1021/ac202730d
  • Forbes, M. W.; Nagy, A. M.; Jockusch, R. A. Photofragmentation of and Electron Photodetachment from a GFP Model Chromophore in a Quadrupole Ion Trap. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY 2011, 308 (2–3, SI), 155–166. https://doi.org/10.1016/j.ijms.2011.08.016
  • Yao, H.; Steill, J. D.; Oomens, J.; Jockusch, R. A. Infrared Multiple Photon Dissociation Action Spectroscopy and Computational Studies of Mass-Selected Gas-Phase Fluorescein and 2′,7′-Dichlorofluorescein Ions. JOURNAL OF PHYSICAL CHEMISTRY A 2011, 115 (34, SI), 9739–9747. https://doi.org/10.1021/jp201946a
  • Sagoo, S. K.; Jockusch, R. A. The Fluorescence Properties of Cationic Rhodamine B in the Gas Phase. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY 2011, 220 (2–3), 173–178. https://doi.org/10.1016/j.jphotochem.2011.04.008
  • Forbes, M. W.; Jockusch, R. A. Gas-Phase Fluorescence Excitation and Emission Spectroscopy of Three Xanthene Dyes (Rhodamine 575, Rhodamine 590 and Rhodamine 6G) in a Quadrupole Ion Trap Mass Spectrometer. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY 2011, 22 (1), 93–109. https://doi.org/10.1007/s13361-010-0017-4
  • Braz, V. A.; Barkley, M. D.; Jockusch, R. A.; Wintrode, P. L. Efavirenz Binding Site in HIV-1 Reverse Transcriptase Monomers. BIOCHEMISTRY 2010, 49 (49), 10565–10573. https://doi.org/10.1021/bi101480z
  • Talbot, F. O.; Rullo, A.; Yao, H.; Jockusch, R. A. Fluorescence Resonance Energy Transfer in Gaseous, Mass-Selected Polyproline Peptides. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2010, 132 (45), 16156–16164. https://doi.org/10.1021/ja1067405
  • Bian, Q.; Forbes, M. W.; Talbot, F. O.; Jockusch, R. A. Gas-Phase Fluorescence Excitation and Emission Spectroscopy of Mass-Selected Trapped Molecular Ions. PHYSICAL CHEMISTRY CHEMICAL PHYSICS 2010, 12 (11), 2590–2598. https://doi.org/10.1039/b921076h
  • McQueen, P. D.; Sagoo, S.; Yao, H.; Jockusch, R. A. On the Intrinsic Photophysics of Fluorescein. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2010, 49 (48), 9193–9196. https://doi.org/10.1002/anie.201004366
  • Forbes, M. W.; Jockusch, R. A. Deactivation Pathways of an Isolated Green Fluorescent Protein Model Chromophore Studied by Electronic Action Spectroscopy. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2009, 131 (47), 17038+. https://doi.org/10.1021/ja9066404
  • Forbes, M. W.; Bush, M. F.; Polfer, N. C.; Oomens, J.; Dunbar, R. C.; Williams, E. R.; Jockusch, R. A. Infrared Spectroscopy of Arginine Cation Complexes: Direct Observation of Gas-Phase Zwitterions. JOURNAL OF PHYSICAL CHEMISTRY A 2007, 111 (46), 11759–11770. https://doi.org/10.1021/jp074859f
  • Forbes, M. W.; Jockusch, R. A.; Young, A. B.; Harrison, A. G. Fragmentation of Protonated Dipeptides Containing Arginine. Effect of Activation Method. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY 2007, 18 (11), 1959–1966. https://doi.org/10.1016/j.jasms.2007.08.003
  • Bush, M. F.; Forbes, M. W.; Jockusch, R. A.; Oomens, J.; Polfer, N. C.; Saykally, R. J.; Williams, E. R. Infrared Spectroscopy of Cationized Lysine and ε-N-Methyllysine in the Gas Phase:: Effects of Alkali-Metal Ion Size and Proton Affinity on Zwitterion Stability. JOURNAL OF PHYSICAL CHEMISTRY A 2007, 111 (32), 7753–7760. https://doi.org/10.1021/jp071902q